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Pathology Haematology 566e8ba3

bcl2 in B-cell lymphoma the translocation involving-

A
t (8 : 14)
B
t (8 :12)
C
t(14:18)
D
t(14 : 22)
High-Yield Explanation
In all follicular lymphomas ,the tumour cells are positive for pan-B markers such as CD19& CD20 along with expression of BCL2 protein .Cytogenic studies show characteristic translocation t(14;18) in tumor cells. Ref: Harshmohan textbook of pathology pg 356

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