Pediatrics General 5662ebfe All of the following are true of ß thalassemia major, except A Increased osmotic fragility B Target cells on peripheral smear C Microcytic hypochromic anemia D Splenomegaly High-Yield Explanation in thalassemia major there will be marked splenomegaly,hypochromic microcytic anemia and target cells in peripheral smear.osmotic fragility decreases