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Pathology Mechanisms of Cell Injury 557547fc

Fenton reaction leads to free radical generation when -

A
Radiant energy is absorbed by water
B
H202 is formed by myeloperoxidase
C
Ferrous ion converted to ferric ion
D
Nitric oxide is converted to peroxynitrite
High-Yield Explanation
Ans. is 'c' i.e., Ferrous ions converted to ferric ions o Free radicals are generated through Fenton's reaction.o In this reaction iron is converted from its ferrous to ferric form and a free radical is generated,o The effect of these reactive species relevant to cells injury include;Lipid peroxidation of membranesOxidative modification of proteins and lesions in DMA.

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