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Anatomy Other topics and Adverse effects 55648f75

. All of the following statements about the use of spironolactone in CHF are true except

A

It should be administered in low doses to prevent hyperkalemial

B

It affords prognostic benefit in severe hea failure over and above that afforded by ACE inhibitors

C

It helps to overcome the refractoriness to thiazides

D

It affords rapid symptomatic relief in CHF patients

High-Yield Explanation

(Ref KDT 6/e p507) Loop diuretics are used to provide rapid symptomatic relief whereas aldosterone antagonists decrease the moality by reversing myocardial remodeling

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