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Medicine Virology 5503fa59

Infection with HIV is associated with atrophy in all of the following parts of the brain except:

A
Anterior cingulate gyrus
B
Globus pallidus
C
Caudate nucleus
D
Lower white matter volume
High-Yield Explanation
Ans. a. Anterior cingulate gyrus (Ref: Harrison 19/e p1264, 1265, 18/e p1559, 1560, 3427)AIDS causes subcortical dementia, involves white matter and causes progressive multifocal leukoencephalopathy and main feature is demyelination.Overall cerebral atrophy and prominent caudate region atrophy are important radiographic features of HIV dementia.HIV-associated dementiaHIV encephalopathy: 'subcortical dementia' characterized by defects in short-term memory and executive functionAIDS causes subcortical dementia, involves white matter and causes progressive multifocal leukoencephalopathy and main feature is demyelination.Overall cerebral atrophy and prominent caudate region atrophy are important radiographic features of HIV dementia.

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