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Pharmacology Autonomic nervous system 54d33e6d

Botulinum toxin produces skeletal muscle paralysis by:

A
Enhancing release of norepinephrine
B
Inhibiting release of acetylcholine
C
Direct damage to nerve endings
D
Producing hemolysis
High-Yield Explanation
Ref: KD Tripathi pharmacology 7th edition (page.no: 99) Botulinum toxin A and B are highly potent exotoxins produced by Clostridium botulinum that is responsible for Botulism. These neurotoxic proteins cause long-lasting loss of cholinergic transmission by interacting with an axonal protein involved in the exocytic release of Ach

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