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Physiology General 54b69862

Most of the testosterone secreted by the testes exists in the plasma in the form of?

A
Dihydrotestosterone bound to gonadal steroid-binding hormone
B
Free dihydrotestosterone
C
Free testosterone
D
Testosterone bound to sex-steroid-binding globulin
High-Yield Explanation
The majority of circulating testosterone is bound to plasma protein (around 98%), rather than existing in free form. Of this, a majority is bound to a specific sex (or gonadal) steroid-binding protein and a minority is bound to albumin. Dihydrotestosterone is produced from testosterone in the tissues by a specific enzyme, 5-alpha-reductase, rather than circulating in bound or free form.

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