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Surgery Fluid, Electrolyte and Nutrition 54af2754

In a 40-year-old woman receiving TPN for small-bowel fistula, what finding can be attributed to hypophosphatemia?

A
Increased cardiac output
B
Diarrhea
C
Increased energy production
D
Rhabdomyolysis
High-Yield Explanation
Hypophosphatemia results in decreased synthesis of phosphorylated intermediate metabolites such as adenosine triphosphate (ATP), 2, 3-DPG, and cyclic adenosine monophosphate (cAMP). Deficiency can result in erythrocyte membrane instability, WBC dysfunction, platelet dysfunction, congestive hea failure, arrhythmias, weakening of respiration muscles, hemolysis, and rhabdomyolysis.

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