Full 2L QBank
Pathology Kidney disorders 545f2304

A child presented with edema, massive proteinuria and hyperlipidemia. True statement about this condition is:

A
Type of focal segmental GN
B
IgA deposition on basement membrane
C
Foot process of glomerular membrane normal
D
Glomerular function is lost due to loss of polyanionic charge on both sites of glomerular foot process
High-Yield Explanation
Glomerular barrier function depends on the molecular size (the larger, the less permeable) and charge (the more cationic, the more permeable) is done. The anionic moieties present within the capillary wall including the acidic proteoglycans of the GBM and the sialoglycoproteins of epithelial and endothelial cells are responsible for the viually complete exclusion of albumin (also having anionic charge) from the filtrate.

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now