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Gynaecology & Obstetrics General 5445229e

A 28 weeks pregnant multigravida with preeclampsia presented with fulminant signs. Urgent C-section was planned. Best method for the diagnosis of lung maturity is:

A
L/S ratio in amniotic fluid
B
Phosphtidyl glycerol estimation in amniotic fluid
C
Bilirubin in amniotic fluid
D
Amniotic fluid creatinine
High-Yield Explanation
Phosphatidylglycerol (PG) is a minor constituent of surfactant. It begins to increase appreciably in amniotic fluid several weeks after the rise in lecithin. Its presence is more indicative of fetal lung maturity because PG enhances the spread of phospholipids on the alveoli. Ref: Mehta S.H., Sokol R.J. (2007). Chapter 13. Methods of Assessment for Pregnancy at Risk. In A.H. DeCherney, L. Nathan (Eds), CURRENT Diagnosis & Treatment Obstetrics & Gynecology, 10e.

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