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Pathology General 5408f3d8

Piecemeal necrosis on liver biopsy is a feature of -

A
Alcoholic hepatitis
B
Indian childhood cirrhosis
C
Chronic active hepatitis
D
Primary alcoholic cirrhosis
High-Yield Explanation
Pathological features of chronic active hepatitis There is active continuous necrosis of liver cells leading to following features. Portal tracts show severe chronic inflammation with inflammatory cells extending into the liver lobules disrupting the limiting plate of hepatocytes. Piecemeal necrosis    Portal fibrosis Bridging necrosis Interface hepatitis Pathological features of chronic persistent hepatitis (Chronic minimal hepatitis) Portal chronic inflammation is mild and restricted to the portal triads, there is no disruption of the limiting plates. Little or no necrosis Minimal fibrosis.

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