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Medicine General 53c8a1ff

Pancreatitis, pituitary tumor and phaeochromocytoma may be associated with which of the following type of thyroid cancer?

A
Anaplastic carcinoma of thyroid
B
Medullary carinoma of thyroid
C
Papillary carcinoma of thyroid
D
Follicular carcinoma of thyroid
High-Yield Explanation
A MEN 1, or Wermer's syndrome, is inherited as an autosomal dominant trait. This syndrome is characterized by neoplasia of the parathyroid glands, enteropancreatic tumors, anterior pituitary adenomas, and other neuroendocrine tumors with variable penetrance. Among the types of thyroid cancer given in the question stem, medullary carcinoma of the thyroid is associated with multiple endocrine neoplasia syndrome. Ref: Harrison's Internal Medicine, 18th Edition, Chapter 351

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