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Pathology JIPMER 2018 53b4dfd9

Which antibody is associated with reduced risk of lupus nephritis in SLE?

A
Anti-ribosomal P antibody
B
Anti-histone antibody
C
Anti-La antibody
D
ANA
High-Yield Explanation
Antibodies associated with SLE :- ANA:- most sensitive Anti ribosomal P ab:- Psychosis/Depression in SLE Anti Ro (SSA) (Anti La Ab:- Nephroprotective Anti Ro Ab :- High chance of :- Subacute cutaneous lupus. Neonatal lupus (a/w congenital Hea Block). Sicca syndrome Anti ds DNA/Anti SM Ab:- Highly specific. Anti histone Ab:- Drug induced lupus.

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