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Gynaecology & Obstetrics Medical & Surgical Illness Complication Pregnancy 538a0732

True about diabetes in pregnancy are all except:

A
Glucose challenge test is done between 24-28 weeks
B
50 gm of sugar is given for screening test
C
Insulin resistance improves with pregnancy
D
Diabetes control before conception is important to prevent malformation
High-Yield Explanation
Ans. is c, i.e. Insulin resistance improves with pregnancyRef. Dutta 7/e, p 282 for option a, b, 283 for option c and 285 for option d; Fernando Arias 3/e, p 440, 442, 443In pregnancy, the insulin sensitivity decreases i.e. insulin resistance increases as the gestation advances mainly due to anti insulin signals produced by placenta (mainly human placental lactogen).Congenital malformations in a diabetic mother occur within first 8 weeks of gestation when most women are just beginning prenatal care. Therefore preconceptional counselling is very essential in a diabetic motherScreening for diabetes during pregnancy is done by glucose challenges test at 24-28 weeks of pregnancy.

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