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Pediatrics New born infants 5353c8a0

Which of the following malformation in a newborn is specific for maternal insulin dependent diabates mellitus ?

A
Transposition of great aeries
B
Caudal regression
C
Holoprosencephaly
D
Meningomyelocele
High-Yield Explanation
Caudal regression syndrome or sacral agenesis ( which is very rare ) is the congenital defect which is specific for maternal insulin dependent diabates mellitus. It is the abnormal fetal development of the lower spine--the caudal paition of the spine. Reference : page 243 Textbook of Obstetrics Sheila Balakrishnan 2nd edition

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