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Pediatrics Childhood tumors 52e42883

Non specific esterase is positive in all the categories of AML except

A
M3
B
M4
C
M5
D
M6
High-Yield Explanation
Non specific esterase on cytochemistry is strongly positive in M5(acute monocytic leukemia- Schilling type) and M4(acute myelomonocytic leukemia -Naegeli type) which have monocytic component.It is also positive in M3(acute promyelocytic leukemia).But non specific esterase is negative in M6(acute erythroleukemia-Di Guglielmo's syndrome),which shows positive for Periodic acid-Schiff. Reference:Textbook of pathology-Harsh Mohan,6th edition,page no:362.

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