False positive ELISA for HIV -
High-Yield Explanation
False positive ELISA is seen in -
Antibodies to class II antigens - Recent influenza vaccination
Auto antibo dies - Acute viral infections
Hepatic disease - Connective tissue diseases e.g. SLE.
ELISA is the standard screening test for HIV infection
It has a sensitivity of > 99.5%, while it is highly sensitive, it is not optimal in regard to specificity.
Most commonly used confirmatory test for the diagnosis of HIV infection - a Western Blot test