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Pathology General 51fce9a1

Cardiac myxoma most common seen in ?

A
Right Atrium
B
Right Ventricle
C
Left Atrium
D
Left Ventricle
High-Yield Explanation
Ans. is 'c' i.e., Left AtriumCardiac myxomasMost common primary tumor of the adult hea.Benign neoplasms thought to arise from primitive multipotentmesenchymal cells.Familial syndromes associated with myxomas have activating mutations in the GNAS1 gene, encoding a subunit of G protein (Gsa) (in association with McCune-Albright syndrome) or null mutations in PRKAR1A, encoding a regulatory subunit of a cyclic-AMP- dependent protein kinase (Carney complex).About 90% of myxomas arise in the atria, with a left-to-right ratio of approximately 4 : 1.

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