Pharmacology General 51af9d9e Most common cytochrome associated with metabolism of drugs is ? A CYP3A4/5 B CYP2D6 C CYP2C8/9 D CYP2Cl.9 High-Yield Explanation Ans. is 'a' i.e., CYP3A4/5 Cyp 3 A 4/5 carryout biotransformation of largest number (nearly 50%) of drugs.