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Gynaecology & Obstetrics Fetus Placenta & Fetal Membrane 51a0dc26

What is the main product of fetal adrenal gland?

A
Cortisol
B
DHEA-S
C
Testosterone
D
Progesterone
High-Yield Explanation
Ans. is b, i.e. DHEA-SMain product of fetal adrenal gland is DHEA-S which it synthesises using cholesterol.The fetal DHEA-S is then used by placenta to synthesize estrogen (E3 and E2 )Extra EdgeAt term, fetal adrenal glands weigh the same as those of adults.More than 80% of fetal gland is composed of unique fetal zone which has a great capacity for steroid synthesis.Daily steroid production of fetal adrenal gland is 100-200 mg/day as compared to adults 30-40 mg/day.Fetal zone is lost in the first year of life and is not present in adults.In anencephaly, fetal adrenal gland is absent or hypoplastic.

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