Pharmacology General 5194b7db

A patient of parkinsonism is managed with L-dopa. If Vit. B-complex is administered concurrently-

The action of L-dopa in brain will be potentiated

Decarboxylation of L-dopa in brain will be decreased

Side effects will be ameliorated

Decreased efficacy will result

High-Yield Explanation

Ans. is 'd' i.e., Decreased efficacy will result "Pyridoxine abolishes the therapeutic effect of levodopa by enhancing peripheral decarboxylation of levodopa".

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