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Pharmacology General 51873c3e

Which of the following combinations will show vasomotor reversal of Dale

A
Phentolamine followed by adrenaline
B
Propanalol followed by adrenaline
C
Phentolamine followed by nor adrenaline
D
Propanalol followed by nor adrenaline
High-Yield Explanation
Adrenaline leads to increased BP by acting on α1 - receptors, and  vasodilation by action on β2 receptors. If it is administered after Phentolamine (α1 - blocker) it can lead to only vasodilation, which is termed as "Vasomotor reversal of Dale".

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