Which Viral Infection associated with Exacerbation of Asthma in COPD Patients

ANSWER: (D) Rhino + RSV + InfluenzaREF: Harrison's 18th ed ch 260Viral respiratory infections are present in approximately one-third of COPD exacerbations >> Rhinovirus may cause exacerbations of asthma and chronic pulmonary disease in adults.Coronaviruses other than SARS-Co V have been recovered occasionally from infants with pneumonia and from military recruits with lower respiratory tract disease and have been associated with worsening of chronic bronchitisSinusitis, otitis media, and worsening of chronic obstructive and reactive airway disease have also been associated with HRSV infectionOther pulmonary complications associated with influenza include worsening of chronic obstructive pulmonary disease and exacerbation of chronic bronchitis and asthmaBacteria frequently implicated in COPD exacerbations include Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. In addition, Mycoplasma pneumoniae or Chlamydia pneumoniae are found in 5-10% of exacerbations