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Medicine Oncology 5131f7aa

Best treatment for glioblastoma multiforme:

A
Chemotherapy
B
Radiation
C
Excision with radiation
D
Stereotactic surgery
High-Yield Explanation
Ans. C. Excision with radiation* These are highly infiltrative tumors, and the areas of increased T2/FLAIR signal surrounding the main tumor mass contain invading tumor cells.* Treatment involves maximal surgical resection followed by partial-field external beam radiotherapy (6000cGy in thirty 200-cGy fractions) with concomitant temozolomide, followed by 6-12 months of adjuvant temozolomide

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