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Medicine Tumors of Nervous System 50dd0bde

Most common tumour of pituitary' is -

A
Prolactinoma
B
GH secreting adenoma
C
ACTH secreting adenoma
D
TSH secreting adenoma
High-Yield Explanation
Ans. is 'a' i.e., Prolactinoma Types of adenomasSecretionStainingPathology% of hormone production casesLacto trophicadenomas(prolactinomas)Secrete prolactinAcidophilicGalactorrhea, hypogonadism, amenorrhea, infertility, and impotence30%SomatotrophicadenomasSecrete growth hormone (GH)AcidophilicAcromegaly in adults; gigantism in children15%CorticotrophicadenomasSecrete adenocorticotropic hormone (ACTH)BasophilicCushing's disease10%GonadotrophicadenomasSecrete luteinizing hormone (LH), follicle stimulating hormone (FSH) and their subunitsBasophilicUsually doesn't cause symptoms10%Thyrotrophic adenomas (rare)Secrete thyroid-stimulating hormone (TSH)Basophilic to chromophobicOccasionally hyperthyroidism, usually doesn't cause symptomsLess than 1%Null cell adenomasDo not secrete hormonesMay stain positive for synaptophvsin 25% of pituitary' adenomas are nonsecretive

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