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Pediatrics General 50a38629

Which of the following is the least common cause of ambiguous genitalia in a female child?

A
Fetal placental steroid sulfatase deficiency
B
Fetal placental aromatase deficiency
C
Congenital adrenal hyperplasia
D
WNT-4 gene mutation
High-Yield Explanation
Fetal placental steroid sulfatase deficiency is an X-linked disorder therefore occur only in males. So it's the least common cause of ambiguous genitalia in a female child. Ref: Principles and practice of endocrinology and metabolism, Page 957 By Kenneth L. Becker page1061.

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