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Pediatrics Other hea diseases in children 5041af6f

Most common gene involved in Noonan syndrome

A
PTCN 11
B
PTPN 11
C
PTPN 22
D
PTCN 22
High-Yield Explanation
NOONAN SYNDROME: - Autosomal dominant, Normal karyotype - MC gene involved --> PTPN 11 - Seen in both boys & girls --> FEILE - FEATURES: Sho stature webbed neck Anti-mongoloid slant eyes (Opposite of Down syndrome) Cubitus valgus Clinodactyly, Cryptorchidism cardiac anomalies: Supra valvular Pulmonary Stenosis -->, HOCM, ASD Presence of Intellectual disability

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