Full 2L QBank
Pharmacology Cardiovascular system 5007ba16

The positive inotropic effect of digitalyzers is due to invitation of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to

A
Decrease the activity of Na+/Ca+ exchanger causing decrease the influx of sodium and decreased efflux of Ca++ in the sarcolemma
B
Decreased efflux of Na+ leading to less negative resting membrane potential and opening of voltage gated Ca+ + channels on the T tubules
C
Increased intracellular Na+ causing increased efflux of any place and increase the influx of Ca + + through Na+/ Ca + + exchanges in sarcolemma
D
Increased intracellular Na+ decreasing the activity of Ca + + pump in the sarcoplasmic reticulum
High-Yield Explanation
Ref-Goodman and Gillman 12/e p802,803 The positive inotropic effect of digitalis is due to inhibition of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to decreased activity of Na+/Ca++ exchanger causing decrease the influx of sodium and decreased efflux of CA++ in the sarcolemma
← Previous Question Next Question →

Related Pharmacology MCQs

Which of the following is glucocoicoid synthesis inhibitor?
General
At a high altitude of 3000 m, a person complains of breathlessness. All of the following can...
General
All of the following drugs act on cell membrane except:
General
A non-competitive inhibitor of an enzyme?
General
Which of the following is a phase I metabolic reaction?
General
Explore All Pharmacology Questions →

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now