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Pharmacology Asthma 4fc04b16

Theophylline levels are increased in all, except

A
Erythromycin
B
Smoking
C
Cimetidine
D
CHF
High-Yield Explanation
Ans. is 'b' i.e., Smoking Smoking induces theophylline metabolism and decreases its plasma level.In certain conditions theophylline concentration is increased, so its dose has to be reduced.These conditions are - Age > 60 years CHFPneumonia Liver failureDrugs causing increased concentration of theophyllineErythromycinCiprofloxacinCimetidineOral contraceptivesAllopurinol

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