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Pathology General 4fbfc4e1

In reflux nephropathy, glomerular lesion is?

A
Focal GN
B
Membranous GN
C
Membrano proliferative G.N
D
Minimal change disease
High-Yield Explanation
Ans. is 'a' i.e., Focal G.NFocal segmental glomerulosclerosis o Focal segmental glomerulosclerosis is characterized by sclerosis of -(i) Some, but not all, glomeruli (thus, it is focal)(ii) In the affected glomeruli, only a poion of capillary tuft is involved (thus, it is segmental). o Clinically it presents as nephrotic syndrome.CausesHIV infection 3. Sickle cell disease 5. IgA nephropathy 7. IdiopathicHeroin addiction 4. Massive obesity 6. Reflux nephropathy

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