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Pharmacology General 4fb6229e

Following is false about aripiprazole except ?

A
Only antipsychotic with D1 agonistic activity
B
It has 5HT1A antagonistic action
C
It has maximum sedating potential
D
It is the drug of choice in treatment of acute mania
High-Yield Explanation
Ans. is `d' i.e., It is the drug of choice in treatment of acute mania Atypical antipsychotics --> Olanzapine, risperidone, aripiprazole or quetiapine with or without benzodiazepine is the treatment of choice for acute mania. Aripiprazole Only antipsychotic with D2 agonistic activity. (all others are D2 antagonists). Longest acting It also has 5HT,A agonistic and 5HT2 antagonistic activity - Also known as dopamine-serotinine stabilizer. It is least sedating antipsychotic - can cause insomnia.

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