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Pharmacology General 4faac488

Alkalinization of urine is done during administration of which of the folloiwng chemotherapeutic drugs?

A
Ara-C
B
Methotrexate
C
Cisplatin
D
Ifosafamide
High-Yield Explanation
Ans is 'b' i.e. Methotrexate o Urine alkalinization by NaHCO3 enhances the elimination of weak acids, e.g. Salicylates, Phenobarbitone, Chlorpropamide, formic acid and methotrexate.

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