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Pharmacology CHF, Angina Pectoris and Myocardial Infarction 4f8dcc99

Digitalis is used in the treatment of acute CHF. It can also be used as a long-term maintenance therapy if CHF is associated with:

A
Hypeension
B
Hyperophic obstructive cardiomyopathy
C
Atrial fibrillation
D
Mitral stenosis
High-Yield Explanation
Digitalis- controlling VR (ventricular rate) in (AF +/- CHF). It can't cure/reve AF to sinus rhythm. It | VR by |ing no. of impulses that pass down the A-V node(AVN)+ bundle of His. | ERP of AVN by vagomimetic + antiadrenergic actions: | min. interval b/w consecutive impulses that can traverse conducting tissue. Long ERP of AVN - many atrial impulses (~500/min) falling in the RRP get extinguished by decremental conduction (concealed impulses)

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