A 40-year-man, working in farm, presented with headache, malaise, sense of tightness in chest, dimness of vision. On examination he had pinpoint pupils. Likely diagnosis is

Ans. a (OP poisoning). (Ref. Parikh, textbook of FMT, 5th/71, 6th/813)Signs & SymptomsDhathura poisoningDryness of mouth & throat, dysphagia, dilated pupils, dry hot skin (fever), delirium, drowsiness & irritability.Lead poisoningMetallic taste, dry throat, nausea & vomiting, thirst, colic pain in abdomen, purging with constipation, headache, drow siness, paralysis of limbs, finally collapse precedes death.OP poisoningAffects first involuntary muscles & secretory glands, then voluntary muscles, & finally vital brain centers.OP PoisoningHeadache, malaise, sense of tightness in chest, diminision of vision, pin-point pupils, nausea, abdominal cramps, vomiting, diarrhea, profuse sweating, salivations and feeling of well being & pleasure, due to inhibition of higher controls (stage of excitement) are important features.# Salivation- # Lacrimation # Urinary incontinence --(Mnemonic: SLUDGE)# Decreased heart rate# Gastro-intestinal symptoms # Elation and excessive sweating-