Microbiology
Immunology Pa 1 (Immune Response, Antigen-Antibody Reactions, Hypersensitivity, Structure of Immune System, Immunodeficiency Disorders)
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Recurrent Neisseria infections are not predisposed by-
High-Yield Explanation
Option 1, 2, 3, 4 Inherited or acquired deficiency of C5-8 (late components) components greatly enhances susceptibility to Neisseria bacteremia and other infections. Deficiency of C3 leads to severe recurrent pyogenic sinusitis and respiratory infections. Deficiency of Properdin and factor D (Alternative pathway Deficiency) lead to Neisserial infection and pyogenic infections. Early complement component (C1, C2, C3, C4) deficiency: SLE, glomerulonephritis and pyogenic infections.