Activated protein C is used therapeutically in:

Answer is option4, sepsis Human recombinant activated protein C for severe sepsis. Mai-Carvajal AJ1, Sola I, Lathyris D, Cardona AF. Author information Update in Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients. Abstract BACKGROUND: Sepsis is a common and frequently fatal condition. Human recombinant activated protein C (APC) has been used to reduce the high rate of death by severe sepsis or septic shock. This is an update of a Cochrane review (originally published in 2007 and updated in 2008).