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Biochemistry TCA Cycle 4eb6158a

All of the following TCA cycle enzymes are located in the mitochondrial matrix, EXCEPT

A
Alpha-ketoglutarate dehydrogenase
B
Isocitrate dehydrogenase
C
Succinate dehydrogenase
D
Malate dehydrogenase
High-Yield Explanation
Ans. c)Succinate dehydrogenase * All the TCA cycle enzymes are present in the mitochondrial matrix except succinate dehydrogenase (complex II of ETC) * Succinate dehydrogenase is embedded in the inner mitochondrial membrane. NOTE: Complex I pumps 4 protons. Complex II doesn't pump any proton. Complex III pumps 4 protons. Complex IV pumps 2 protons.

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