True statement regarding development of drug resistance in MRSA is?
High-Yield Explanation
MRSA have emerged in many areas. These are insensitive to all penicillinase-resistant penicillins and to other beta-lactams as well as to erythromycin, aminoglycosides, tetracyclines, etc. The MRSA have altered PBPs which do not bind penicillins. ESSENTIALS OF MEFICAL PHARMACOLOGY page no 721