Histologic examination of the lesion in stomach reveal fat-laden cells, likely cause is -

Lipid-laden macrophages (foam cells) are seen in xanthomatosis of the stomach. Xanthomatosis of stomach It is characterized by a collection of lipid-laden macrophages (foam cells), forming plaques or nodules. Gastric xanthomatosis is more common in patients with : - 1. Gastritis 2. Gastric ulcer  3. Deudenogastric reflux after gastric surgery.