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Pharmacology General 4e613b22

Brinzolamide is a

A
Highly specific irreversible and noncompetitive carbonic anhydrase inhibitor
B
Highly specific irreversible and competitive carbonic anhydrase inhibitor.
C
Highly specific reversible and competitive carbonic anhydrose inhibitor
D
Highly specific reversible and non-competitive carbonic anhydrase inhibitor.
High-Yield Explanation
Ans is 'd' i.e. Highly specific reversible and noncompetitive carbonic anhydrase inhibitor o Carbonic anhydrase inhibitors act by a non-competitive, reversible inhibition of the enzyme carbonic anhydrase. o Brinzolamide is a highly .specific inhibitor of carbonic anhydrase II (CA II), which is the main carbonic anhydrase isoenzyme involved in the secretion of aqueous humour. o Inhibition caused by brinzolamide is reversible and non-competitive.

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