Allergic hypersensitivity is mediated by -
High-Yield Explanation
Atopy or allergic hypersensitivity is type I which is mediated by IgE. Atopic sensitivity is due to overproduction of IgE antibodies. In normal individuals , the inhalent and ingested antigens are delt with IgA lining the respiratory and intestinal mucosa and thus do not come in contact with IgE producing cells. When IgA is deficient, antigen cause massive stimulation of IgE forming cells leading to overproduction of IgE. Reference : Anathanarayan & paniker's 9th edition, pg no:165 <\p>