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Medicine General 4d71d7f6

All of the following are true about Cushing's syndrome, Except

A
Red striae
B
Increased adrenaline
C
Proximal muscle weakness
D
Edema
High-Yield Explanation
Answer is B (Increased adrenaline): Cushing's syndrome results from an excessive amount of coicosteroids secreted from the adrenal coex (outer pa) of the adrenal gland. Adrenaline is secreted from the adrenal medulla (inner pa) of the gland and is not raised in Cushing's syndrome. Increased adrenaline is a feature of adrenal medullary disorders like pheochromocytoma. Red striae may be seen in Cushing Syndrome Red or purplish 'violaceous' striae are typical of Cushing's syndrome -- William's Endocrinology Proximal muscle weaknes may be seen in Cushing's syndrome 'The myoputhy of Cushing's syndrome typically involves the proximal muscles of lower limbs or shoulder girdle' -- William's Endocrinology Edema may be seen in Cushing's syndrome Edema is seen in about 60% of patients with Cushing's syndrome. This is believed to result from mineralocoicoid action, because glucocoicoids in high concentrations have mineralocoicoid action.

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