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Gynaecology & Obstetrics All India exam 4d3aed15

Which of the following is true regarding RU 486?

A
Prevents feilization
B
Has affinity for estrogen receptors
C
Single dose of 10mg prevents pregnancy in 90% cases
D
Causes delayed menstruation
High-Yield Explanation
RU 486 (mifepristone) does not prevent feilization. It has affinity for progesterone receptors. It blocks the action of progesterone on the endometrium. It prevents implantation by causing sloughing and shedding of decidua. Single dose of 10mg prevents pregnancy in 99.1% cases. Ref: Shaw's Textbook of Gynaecology, 18th edition, p237

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