Pharmacology Other topics and Adverse effects 4d3a5d89 Which of the following drugs inhibits de nove synthesis of purines? A Cyclosporine B Tacrolimus C Mycophenolate D Infliximab High-Yield Explanation (Ref: KDT 6/e p841) By inhibiting the enzyme IMP dehydrogenase, mycophenolate inhibits the de novo synthesis of purines.