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Pathology Cytogenetic Disorders 4c8a6b65

Hereditary retinoblastomas develop the following chromosomal detection?

A
13ql4
B
13pl4
C
14pl3
D
14ql3
High-Yield Explanation
Ans. (a) 13q14Ref: Robbin's pathology 9th ed./1359* Wilm's tumor-Aniridia complex (WAGR syndrome)11 p 13 part of (deletion of short arm of chromosome)* Retinoblastoma13q 14.11 (deletion of part of long arm of chromosome 13)* Prader-Willi syndrome Angelman syndrome15q 11-13 (deletion of part of long arm of chromosome 15)* DiGeorge's syndrome Velo-Cardio-facial syndrome22qll (deletion of part of long arm of chromosome -22)

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