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Physiology Nervous System 4c6b0670

Which cerebellar component would be abnormal in a degenerative disease that affected spinal sensory neurons?

A
Purkinje cells
B
Mossy fibers
C
Parallel fibers
D
Climbing fibers
High-Yield Explanation
Ans. B. Mossy fibersSpinal input, such as from the spinocerebellar tracts, enters the cerebellum on the mossy fibers. The climbing fibers originate from the inferior olivary nucleus of the medulla (the olivo-cerebellar tract). The other components are intrinsic to the cerebellum.Diagram of neural connections in the cerebellum. Plus (+) and minus (-) signs indicate whether endings are excitatory or inhibitory. BC, basket cell; GC, Golgi cell; GR, granule cell; NC, cell in deep nucleus; PC, Purkinje cell.

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