Anatomy Development of nervous system and cerebrum 4c0b678a Which of the following structures is derived from the telencephalon? A Pineal gland B Hypothalamus C Hippocampus D Optic nerve (CN II) High-Yield Explanation The hippocampus develops from telencephalon. The pineal gland, hypothalamus, CN II, and globus pallidus are derived from the diencephalon.