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Medicine Disorders of Adrenal Gland 4bf9df44

Hypokalemic Hypeension is a feature of?

A
Bater syndrome
B
Gitelman syndrome
C
Grave's disease
D
Liddle syndrome
High-Yield Explanation
Liddle syndrome: Is a defect in aldosterone receptor ENaC which exhibits a reduced degradation and results in channel being in open configuration for a longer duration. This enhances mineralocoicoid action and leads to enhanced urinary loss of potassium. Choice A and B have normal to low BP since both have salt wasting. Grave's will cause hypeension due to intrinsic sympathomimetic action of thyroid hormones. However there is no electrolyte imbalance.

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