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Medicine Immunology and Rheumatology 4bda80d5

A 25 years old female develops serous otitis media of left ear with cough and occasional hemoptysis and hematuria and epistaxis for one and half months her. Hemoglobin is 7 gm. B.P. > 170/100, proteinuria +++, RA positive (+ve) and ANCA positive (+ve), the likely cause is:

A
Wegener's granulomatosis
B
Rheumatoid arthritis
C
Rapidly proliferative glomerulonephritis
D
Good Pasteur's syndrome
High-Yield Explanation
Ans. A. Wegener's granulomatosisa. Any vasculitic lesion involving upper respiratory tract, lungs & kidney is characteristic of Wegner'sb. In this case, serous otitis media with hemoptysis, hematuria with C-ANCA positive is diagnostic of Wegner's

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