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Pathology Autoimmune Diseases 4bc5cab5

Thymic hyperplasia is seen in -

A
Thymoma
B
Thymic lymphoma
C
Myasthenia gravis
D
Scleroderma
High-Yield Explanation
Ans. is 'c' i.e., Mysthenia gravis Thymic hyperplasiao The term thymic hyperplasia usually applies to the appearance of B-cell germinal centers within the thymus, a finding that is referred to as thymic follicular hyperplasia.o Such B-cell follicles are present in only small numbers in the normal thymus.o It can occur in a number of chronic inflammatory and immunologic states, but it is most frequently encountered in myasthenia gravis (65% to 75% of cases).o Similar thymic changes are sometimes encountered in Graves disease, systemic lupus erythematosus, scleroderma, rheumatoid arthritis, and other autoimmune disorders.

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